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Tox-Prediction
Here you can search for an input compound via pubchem:
Pubchem-Name:
e.g.
Tamoxifen
Tolcapone
Vorinostat
Troglitazone
Aspirin
Canonical Smiles:
e.g.
CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
Here you can get a tox-prediction for any input compound:
Selected molecule :
Tamoxifen
To load a molecule click
. The
deletes clicked atoms
and
deletes everything on the canvas.
You have to enable JavaScript to use this tool.
Please select any additional models to predict:
(Acute Toxicity is always computed, further models can take ~10s time each)
Organ Toxicity
Hepatotoxicity
Toxicity end points
Carcinogenicity
Immunotoxicity
Mutagenicity
Cytotoxicity
Tox21 Nuclear receptor signalling pathways
Aryl hydrocarbon Receptor (AhR)
Androgen Receptor (AR)
Androgen Receptor Ligand Binding Domain (AR-LBD)
Aromatase
Estrogen Receptor Alpha (ER)
Estrogen Receptor Ligand Binding Domain (ER-LBD)
Peroxisome Proliferator Activated Receptor Gamma (PPAR-Gamma)
Tox21 Stress response pathways
Nuclear factor (erythroid-derived 2)-like 2/antioxidant responsive element (nrf2/ARE)
Heat shock factor response element (HSE)
Mitochondrial Membrane Potential (MMP)
Phosphoprotein (Tumor Suppressor) p53
ATPase family AAA domain containing protein 5 (ATAD5)
All
None